The upper respiratory tract, comprising the nose, mouth, pharynx, and larynx, is a complex anatomical region that plays a crucial role in the process of respiration. To maintain its various functions, the upper respiratory tract requires a rich blood supply and innervation. The blood supply to the upper respiratory tract is provided by a network of arteries that arise from the external carotid artery, while the innervation is provided by a combination of cranial nerves and sympathetic and parasympathetic nerves.
Blood Supply
The blood supply to the upper respiratory tract is derived from the external carotid artery, which gives rise to several branches that supply the different regions of the upper respiratory tract. The maxillary artery, a major branch of the external carotid artery, supplies the nasal cavity, pharynx, and larynx. The maxillary artery gives rise to the sphenopalatine artery, which supplies the nasal cavity, and the descending palatine artery, which supplies the pharynx. The lingual artery, another branch of the external carotid artery, supplies the tongue and the floor of the mouth. The facial artery, also a branch of the external carotid artery, supplies the lips, nose, and surrounding tissues.
Innervation
The innervation of the upper respiratory tract is provided by a combination of cranial nerves and sympathetic and parasympathetic nerves. The trigeminal nerve (cranial nerve V) provides sensory innervation to the nasal cavity, pharynx, and larynx. The trigeminal nerve has three branches: the ophthalmic, maxillary, and mandibular branches. The ophthalmic branch supplies the nasal cavity, while the maxillary branch supplies the pharynx. The mandibular branch supplies the lower lip, the floor of the mouth, and the tongue.
The facial nerve (cranial nerve VII) provides motor innervation to the muscles of the face, including the muscles of the nose and mouth. The facial nerve also provides sensory innervation to the tongue and the palate. The glossopharyngeal nerve (cranial nerve IX) provides sensory innervation to the pharynx and the larynx, as well as motor innervation to the stylopharyngeus muscle, which elevates the pharynx during swallowing.
The vagus nerve (cranial nerve X) provides sensory innervation to the larynx and the trachea, as well as motor innervation to the muscles of the larynx, including the cricothyroid muscle, which regulates the tension of the vocal cords. The vagus nerve also provides parasympathetic innervation to the upper respiratory tract, which helps to regulate the secretion of mucus and the constriction of blood vessels.
Sympathetic and Parasympathetic Innervation
The sympathetic and parasympathetic nervous systems play important roles in regulating the functions of the upper respiratory tract. The sympathetic nervous system, which is responsible for the "fight or flight" response, causes the blood vessels of the upper respiratory tract to constrict, reducing blood flow to the region. The parasympathetic nervous system, on the other hand, causes the blood vessels to dilate, increasing blood flow to the region.
The parasympathetic nervous system also regulates the secretion of mucus in the upper respiratory tract. The parasympathetic nerves release acetylcholine, which stimulates the mucous glands to secrete mucus. The sympathetic nervous system, on the other hand, inhibits the secretion of mucus by releasing norepinephrine, which reduces the activity of the mucous glands.
Clinical Significance
The blood supply and innervation of the upper respiratory tract have important clinical significance. Damage to the blood vessels or nerves of the upper respiratory tract can result in a range of symptoms, including nasal congestion, rhinorrhea, and dysphagia. The rich blood supply to the upper respiratory tract also makes it a common site for bleeding, particularly in the case of trauma or surgery.
The innervation of the upper respiratory tract is also important in the diagnosis and treatment of various respiratory disorders. For example, the trigeminal nerve is often involved in the diagnosis and treatment of trigeminal neuralgia, a condition characterized by severe facial pain. The vagus nerve is also important in the diagnosis and treatment of laryngeal disorders, such as vocal cord paralysis.
In conclusion, the blood supply and innervation of the upper respiratory tract are complex and play important roles in maintaining the various functions of the region. Understanding the anatomy and physiology of the blood supply and innervation of the upper respiratory tract is essential for the diagnosis and treatment of various respiratory disorders.





